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How Taltz can
help kids and
teens

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Taltz is a prescription medicine used to treat adults and children six years and older with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light).

Select Important Safety Information

Taltz affects the immune system. It may increase your risk of infections, which can be serious. Do not use Taltz if you have any symptoms of infection, unless your doctor tells you to. If you have a symptom after starting Taltz, call your doctor right away.

TODO

See what’s possible for kids and teens

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Moderate to severe plaque psoriasis can affect kids and teens just as it does adults. It can be especially difficult for children to deal with, which is why clear skin is so important and where Taltz can help.

FOR KIDS AND TEENS AGES 6 AND UP WITH MODERATE TO SEVERE PLAQUE PSORIASIS

FIRST OF ITS KIND*

Taltz is the first treatment of its kind* to offer a chance at 100% clear skin for kids and teens.

*First biologic with 100% clear skin in the label for kids and teens ages 6 and up. 50% of children taking Taltz achieved completely clear skin by week 12.

A CHANCE AT 100% CLEAR SKIN

89% saw a significant improvement of their psoriasis plaques at 12 weeks. 50% even achieved completely clear skin.

Select Safety Information

Your doctor should check you for tuberculosis (TB) before you start Taltz, and watch you closely for signs of TB during and after treatment with Taltz. If you have TB, or had it in the past, your doctor may treat you for it before you start Taltz.

SCALP CLEARANCE DATA

Nearly 7 out of 10 achieved 100% clearance of the scalp in 12 weeks.†

†This information is from a subset of 102 pediatric patients on Taltz from a moderate to severe plaque psoriasis clinical trial who also had psoriasis plaques on their scalp. The analysis of this smaller population was not the main purpose of the clinical trial.

WORKS QUICKLY

In as quickly as 4 weeks, more than half saw significantly clearer skin.

STAY CLEAR

After achieving significant improvement of their psoriasis plaques by week 12, most maintained those results through 12 months with continued treatment.ǂ

ǂAfter completion of the initial 12-week period of the clinical trial, additional data were collected in an extended, less-rigorous study through 48 weeks.

REDUCES ITCH

71% of kids and teens ages 6 and up saw improvement§ in itch severity.ǁ

§When compared to placebo at week 12, as measured by a reduction of at least 4 points on the 11-point Itch Numeric Rating Scale.
ǁAll patients had a baseline rating ≥4 on the Itch Numeric Rating Scale at the time of the study.

A SIGNIFICANT DIFFERENCE

After just 3 months and 4 doses, 89% of kids and teens achieved significantly clearer skin.

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Select Important Safety Information

Do not use Taltz if you have had a serious allergic reaction to ixekizumab or any other ingredient in Taltz, such as: swelling of your eyelids, lips, mouth, tongue or throat, trouble breathing, feeling faint, throat or chest tightness, or skin rash. Get emergency help right away if you have any of these reactions. See the Medication Guide that comes with Taltz for a list of ingredients.

See the difference Taltz can make, check out "before" and "after" images of elbows and knees.

See before and after results

See how Taltz can help adults with psoriasis.

Learn more

SAFETY SUMMARY

Warnings -

Taltz affects the immune system. It may increase your risk of infections, which can be serious. Do not use Taltz if you have any symptoms of infection, unless your doctor tells you to. If you have a symptom after starting Taltz, call your doctor right away.

Your doctor should check you for tuberculosis (TB) before you start Taltz, and watch you closely for signs of TB during and after treatment with Taltz. If you have TB, or had it in the past, your doctor may treat you for it before you start Taltz.

Do not use Taltz if you have had a serious allergic reaction to ixekizumab or any other ingredient in Taltz, such as: swelling of your eyelids, lips, mouth, tongue or throat, trouble breathing, feeling faint, throat or chest tightness, or skin rash. Get emergency help right away if you have any of these reactions. See the Medication Guide that comes with Taltz for a list of ingredients.

Crohn’s disease or ulcerative colitis (inflammatory bowel disease) can start or get worse with Taltz use. Tell your doctor if you have any of these symptoms or if they get worse: stomach pain, diarrhea, and weight loss.

You should not get live vaccines while taking Taltz. You should get the vaccines you need before you start Taltz.

Common side effects
The most common side effects of Taltz include:

  • Injection site reactions
  • Nausea
  • Upper respiratory infections
  • Fungal skin infections

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using

Before you use Taltz, review these questions with your doctor:

❑ Are you being treated for an infection?
❑ Do you have an infection that does not go away or keeps coming back?
❑ Do you have TB or have you been in close contact with someone with TB?
❑ Do you have possible symptoms of an infection such as fever, cough, sores, diarrhea, or other symptoms? Ask your doctor about other possible symptoms.
❑ Do you have Crohn’s disease or ulcerative colitis?

Tell your doctor if:

❑ You need any vaccines or have had one recently.
❑ You take prescription or over-the-counter medicines, vitamins, or herbal supplements.
❑ You are pregnant or planning to become pregnant. It is not known if Taltz can harm an unborn baby. Pregnancy Exposure Registry: There is a pregnancy registry to collect information about women who are exposed to Taltz during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. If you become pregnant while taking Taltz, you are encouraged to enroll in the pregnancy registry by calling 1-800-284-1695 or by visiting online at https://www.taltz.com.
❑ You are breastfeeding or planning to breastfeed. It is not known if Taltz passes into breastmilk.

How to take

See the instructions for use that come with Taltz. There you will find information about how to store, prepare, and inject Taltz. Adults may self-inject after receiving training from a healthcare provider.

For people under 18 years of age:

  • Weighing less than 50 kg (i.e., 110 lb): Taltz must be given by a healthcare provider.
  • Weighing more than 50 kg (i.e., 110 lb): If your healthcare provider decides that your caregiver may give your injections of Taltz at home, your caregiver should ask and receive training from a healthcare provider on the right way to prepare and inject Taltz.

Learn more

Taltz is a prescription medicine. For more information, call 1-800-545-5979 or go to taltz.com.

This summary provides basic information about Taltz but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Taltz and how to take it. Your doctor is the best person to help you decide if Taltz is right for you.

IX CON BS 05OCT2022

Taltz® and its delivery device base are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

INDICATIONS

Taltz® (tȯl-ts) is an injectable medicine used to treat:

  • People 6 years of age and older with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).
  • Adults with active psoriatic arthritis.
  • Adults with active ankylosing spondylitis.
  • Adults with active non-radiographic axial spondyloarthritis with objective signs of inflammation.

It is not known if Taltz is safe and effective in children for conditions other than plaque psoriasis or in children under 6 years of age.