At first use, over 94% of adult patients with moderate to severe plaque psoriasis agreed that the Taltz autoinjector was “easy to use” and were confident in their ability to use it.
To learn how to use Taltz, watch the video or read the Instructions for Use that come with your autoinjector.
Even if you have given yourself and injection before, it is important to know that the Taltz autoinjector has different instructions from any device you may have used in the past.
If you are enrolled in Taltz Together™, a Companion in Care™ can help connect you to a registered nurse who can provide injection support in-home or over the phone. Learn more
For other important administration and preparation instructions, talk to your doctor and refer to the Instructions for Use that come with your device.
Taltz abbreviated steps to inject
Make sure the device is in the lock position.
Twist off the base cap in the direction of the arrows.
Place the base of the device flat and firmly against injection site.
Turn the lock ring to the unlock position.
Press the green injection button.
You will hear a loud click, which means the injection has started.
Listen for a second click about 10 seconds later. The second click means the injection is complete.
Do not remove injector from skin until you’ve heard the second click.
Once you’ve completed the injection, dispose of your device in the Taltz sharps container or another puncture-resistant container with a secure lid. Do not dispose of in household trash.
IMPORTANT: These are not the complete instructions for using the autoinjector. Please see Instructions for Use that come with your device.
When taking Taltz, please remember
- Take your device out of the refrigerator and let it sit for 30 minutes to warm to room temperature. Leave the base cap/cap on the device while it is warming up to room temperature
- You may inject the medicine into your stomach (abdomen) or thigh
- Another person may give you the injection in the back of your arm
- Alternate your injection site. Do not inject in the exact same spot every time
- Do not inject within 1 inch of your belly button
- Do not give an injection into areas where the skin is tender, bruised, red or hard, or in an area of skin that is affected by psoriasis
One of the most common side effects of Taltz is injection site reactions. However, most injection site reactions were mild to moderate and didn’t stop people from taking Taltz.
Before you or your caregiver inject for the first time, your healthcare provider should show you or your caregiver how to prepare and inject Taltz.
Important storage information
Do not use Taltz if it has been frozen.
You should protect Taltz from light at all times.
Do not shake your Taltz device.
Helpful injection tips
Talk to your doctor about whether the tips below may help with the injection of biologics.*
- Placing something cold (such as an ice gel pack or cold water bottle) on the injection site before and after the injection may help reduce pain.
- Acetaminophen may help relieve pain.
- Antihistamines or topical corticosteroids may help with itching or swelling caused by the injection.
- Choose different injection sites each time you inject.
The recommended places for injection are your stomach (abdomen) or thigh, and another person may give you the injection in the back of your arm.
Tips specific to Taltz
- You should take Taltz out of the refrigerator and let it sit for 30 minutes to warm to room temperature before injecting. Leave the cap on the device while it is warming up to room temperature.
- However, Taltz should not be microwaved, run under hot water, or left in direct sunlight.
- There are 2 devices available for injecting Taltz: an autoinjector and a prefilled syringe.
Things to know
You may experience side effects while taking Taltz. If you do, please reach out to your doctor.
Injection site reactions
- Injection site pain may occur while you are injecting. Other reactions, such as redness, may happen after several days
- Most injection site reactions were mild to moderate and did not stop people from taking Taltz
- Talk to your doctor about any injection site reactions
If you are experiencing injection site reactions with one type of device, talk to your doctor about whether it might be appropriate to switch to the other Taltz device.
The other most common side effects include:
- Upper respiratory infections
- Fungal skin infections
These are not all of the possible side effects of Taltz. Serious side effects may occur. Tell your healthcare provider about any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit fda.gov/medwatch or call 1-800-FDA-1088.
Lilly is currently monitoring and will continue to monitor and communicate additional information about injection site reactions. Please contact The Lilly Answers Center at 1-800-LillyRx (1-800-545-5979) if you have more questions about this topic.
Select Safety Information
The most common side effects of Taltz include: injection site reactions, upper respiratory infections, nausea and fungal skin infections. Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.