At first use, over 94% of people with psoriasis agreed the Taltz autoinjector was “easy to use” and were confident in their ability to use it.

How to use

To see how to use Taltz, watch the video or read the Instructions for Use that comes with your Autoinjector.

If you are enrolled in Taltz Together,™ a Companion in Care™ can help connect you to a registered nurse who can provide injection support in-home or over the phone.

For other important administration and preparation instructions, talk to your doctor and refer to the Instructions for Use that come with your device.

Learn more

Taltz abbreviated steps to inject

Step 1

Taking taltz ifu step 1

Make sure the device is in the lock position.

Twist off the base cap in the direction of the arrows.

Step 2

Taking taltz ifu step 2

Place the base of the device flat and firmly against injection site.

Turn the lock ring to the unlock position.

Step 3

Taking taltz ifu step 3

Press the green injection button.

You will hear a loud click, which means the injection has started.

Step 4

Taking taltz ifu step 4

Listen for a second click about 10 seconds later. The second click means the injection is complete.

Do not remove injector from skin until you’ve heard the second click.

Once you’ve completed the injection, dispose of your device in the Taltz sharps container or another puncture-resistant container with a secure lid. Do not dispose of in household trash.

IMPORTANT: These are not the complete instructions for using the autoinjector. Please see Instructions for Use that come with your device.

Taking Taltz logo

When taking Taltz, please remember

  • Take your device out of the refrigerator and let it sit for 30 minutes to warm to room temperature. Leave the base cap/cap on the device while it is warming up to room temperature
  • You may inject the medicine into your stomach (abdomen) or thigh
  • Another person may give you the injection in the back of your arm
  • Alternate your injection site. Do not inject in the exact same spot every time
  • Do not inject within 1 inch of your belly button
  • Do not give an injection into areas where the skin is tender, bruised, red, hard, or in an area of skin that is affected by psoriasis

Before you or your caregiver inject for the first time, your healthcare provider should show you how to prepare and inject Taltz.

Important Storage Information – Store Taltz in the refrigerator and protect from light. Do not freeze Taltz. Do not use Taltz if it has been frozen. Do not shake your Taltz device.

Indications and Important Safety Information

Taltz is a prescription medicine used to treat adults with active psoriatic arthritis. Taltz is also a treatment for adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light).

Important Safety Information
Do not use Taltz if you have had a severe allergic reaction to ixekizumab or any of the other ingredients in Taltz. See the Medication Guide for a complete list of ingredients in Taltz. If you have a severe allergic reaction, do not take another injection of Taltz.
Taltz is a medicine that affects your immune system and may lower the ability of your immune system to fight infections. Taltz may increase your risk of infections, which can sometimes become serious.
  • Your healthcare provider (HCP) should check you for tuberculosis (TB) before you begin treatment with Taltz and may treat you for TB if you have a history of TB or have TB
  • Your HCP should watch you closely for signs and symptoms of TB during and after treatment with Taltz
Before starting Taltz
Before starting Taltz, tell your HCP(s) if you
  • are being treated for an infection
  • have an infection that does not go away or that keeps coming back
  • have or have had TB, or have been in close contact with someone with TB
  • think you have an infection or have symptoms of an infection, such as
    • fever, sweats, or chills
    • muscle aches
    • cough
    • shortness of breath
    • blood in your phlegm (mucus)
    • weight loss
    • warm, red, or painful skin or sores on your body
    • diarrhea or stomach pain
    • burning when you urinate or urinating more often than usual
  • have Crohn’s disease or ulcerative colitis
  • recently received or are scheduled to receive an immunization (vaccine). People who take Taltz should not receive live vaccines. Prior to starting Taltz, consider completion of all age-appropriate immunizations according to current immunization guidelines
  • are pregnant or plan to become pregnant. It is not known if Taltz can harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if Taltz passes into your breast milk
After starting Taltz
After starting Taltz, call your HCP right away if you have any of the symptoms of infection listed above. Do not use Taltz if you have any symptoms of infection, unless you are instructed to by your HCP.
Talk to your doctor
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Serious Side Effects
Taltz may cause serious side effects, including
  • Serious allergic reactions. Get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction:
    • feeling faint
    • swelling of your face, eyelids, lips, mouth, tongue, or throat
    • trouble breathing or throat tightness
    • chest tightness
    • skin rash
  • Inflammatory bowel disease (Crohn's disease or ulcerative colitis) can happen during treatment with Taltz, including worsening symptoms. Tell your HCP if you have new or worsening symptoms of inflammatory bowel disease during treatment with Taltz, including stomach pain, diarrhea (with or without blood in stool), or weight loss
Common side effects
The most common side effects of Taltz include: injection site reactions, nausea, fungal infections, and upper respiratory infections. These are not all of the possible side effects of Taltz. Tell your HCP about any side effect that bothers you or that does not go away.
Additional Information
Call your HCP for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.
Store Taltz in the refrigerator, and protect it from light. Do not freeze Taltz or use Taltz if it has been frozen. Do not shake Taltz.
Taltz is available by prescription only.
Please click to access the full Prescribing Information and Medication Guide. Please click to access Instructions for Use included with your device.