What is Plaque Psoriasis?

Plaque psoriasis is caused by an overactive immune system. Plaque psoriasis is the most common form of psoriasis, which can result in raised, red, silver, or flaky patches on your skin.

Taltz biologic logo
Taltz biologic logo

How does Taltz work for patients with moderate to severe plaque psoriasis?

Interleukin 17A (IL-17A) is one protein in your body that plays a role in inflammation and skin plaque growth. Taltz works to help block IL-17A within your body.*

*The relationship between the mechanism of action and clinical outcomes has not been determined.

Is Taltz right for you?

Taltz is a biologic (injection) prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light).

What is a biologic?
A biologic is a protein-based drug produced from living cells. Biologics are different from traditional systemic drugs that impact the entire immune system. Biologics, instead, target specific parts of the immune system.

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Why Taltz?

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Taltz is the first and only treatment of its kind* that offers a chance at 100% clear skin

*IL-17A antagonist that includes 100% clear skin in the Prescribing Information.

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With Taltz, up to 90% of people saw a significant improvement of their psoriasis plaques. Some* achieved completely clear skin.

*4 out of 10 achieved completely clear skin.

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Taltz works quickly to provide most patients significantly clearer skin by 12 weeks.

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Most people with psoriasis who were significantly clearer at 12 weeks still saw those results more than a year later.

75% of those achieving clear or almost clear skin at 12 weeks maintained those results at 60 weeks.

Visible results

See how quickly Taltz can make a difference in just 12 weeks

90% of patients taking Taltz achieved significantly clearer skin at 12 weeks.

Before treatment

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After treatment

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Illustration of 75% skin clearance at 12 weeks.

Before treatment

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After treatment

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Illustration of 90% skin clearance at 12 weeks.

4 out of 10 patients taking Taltz achieved completely clear skin at 12 weeks.

Before treatment

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After treatment

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Illustration of completely clear skin at 12 weeks.

Photos are for illustrative purposes only and do not depict actual patients. Individual results may vary.

Real patients, real results

A great way to know that a psoriasis treatment works is to hear it from someone who’s experienced success firsthand. Watch below to find out why these patients are glad they are being treated with Taltz.

Individual results may vary.

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Meet Angie, a mom who enjoys watching movies with her husband and has been living with psoriasis for most of her life.

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Meet Ken, a husband who owns and manages a restaurant with his wife and has been living with psoriasis for a few years.

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Meet Cindy, a mom who loves to needlepoint and has been living with psoriasis for almost 20 years.

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Meet Bob, a family man with 6 dogs who has been living with psoriasis for most of his life.


Relief for genital psoriasis is possible

Up to 63% of psoriasis patients experience genital psoriasis at some point during the course of their disease. Genital psoriasis usually affects the penis or outer skin of the vagina. It may appear as thin red plaques/patches that can be smooth or scaly. If you have genital psoriasis, you may be a candidate for a biologic treatment.


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*Most people taking Taltz saw a significant improvement of their genital psoriasis by 12 weeks.


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*Most people taking Taltz reported a considerable reduction of their genital itch at 12 weeks.

Find a dermatologist

Finding the right dermatologist is important. If you need help locating one, please click below for a list of dermatologists provided by the National Psoriasis Foundation.
Indications and Important Safety Information

Taltz is a prescription medicine used to treat adults with active psoriatic arthritis. Taltz is also a treatment for adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light).

Important Safety Information
Do not use Taltz if you have had a severe allergic reaction to ixekizumab or any of the other ingredients in Taltz. See the Medication Guide for a complete list of ingredients in Taltz. If you have a severe allergic reaction, do not take another injection of Taltz.
Taltz is a medicine that affects your immune system and may lower the ability of your immune system to fight infections. Taltz may increase your risk of infections, which can sometimes become serious.
  • Your healthcare provider (HCP) should check you for tuberculosis (TB) before you begin treatment with Taltz and may treat you for TB if you have a history of TB or have TB
  • Your HCP should watch you closely for signs and symptoms of TB during and after treatment with Taltz
Before starting Taltz
Before starting Taltz, tell your HCP(s) if you
  • are being treated for an infection
  • have an infection that does not go away or that keeps coming back
  • have or have had TB, or have been in close contact with someone with TB
  • think you have an infection or have symptoms of an infection, such as
    • fever, sweats, or chills
    • muscle aches
    • cough
    • shortness of breath
    • blood in your phlegm (mucus)
    • weight loss
    • warm, red, or painful skin or sores on your body
    • diarrhea or stomach pain
    • burning when you urinate or urinating more often than usual
  • have Crohn’s disease or ulcerative colitis
  • recently received or are scheduled to receive an immunization (vaccine). People who take Taltz should not receive live vaccines. Prior to starting Taltz, consider completion of all age-appropriate immunizations according to current immunization guidelines
  • are pregnant or plan to become pregnant. It is not known if Taltz can harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if Taltz passes into your breast milk
After starting Taltz
After starting Taltz, call your HCP right away if you have any of the symptoms of infection listed above. Do not use Taltz if you have any symptoms of infection, unless you are instructed to by your HCP.
Talk to your doctor
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Serious Side Effects
Taltz may cause serious side effects, including
  • Serious allergic reactions. Get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction:
    • feeling faint
    • swelling of your face, eyelids, lips, mouth, tongue, or throat
    • trouble breathing or throat tightness
    • chest tightness
    • skin rash
  • Inflammatory bowel disease (Crohn's disease or ulcerative colitis) can happen during treatment with Taltz, including worsening symptoms. Tell your HCP if you have new or worsening symptoms of inflammatory bowel disease during treatment with Taltz, including stomach pain, diarrhea (with or without blood in stool), or weight loss
Common side effects
The most common side effects of Taltz include: injection site reactions, nausea, fungal infections, and upper respiratory infections. These are not all of the possible side effects of Taltz. Tell your HCP about any side effect that bothers you or that does not go away.
Additional Information
Call your HCP for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit fda.gov/medwatch or call 1-800-FDA-1088.
Store Taltz in the refrigerator, and protect it from light. Do not freeze Taltz or use Taltz if it has been frozen. Do not shake Taltz.
Taltz is available by prescription only.
Please click to access the full Prescribing Information and Medication Guide. Please click to access Instructions for Use included with your device.